Chapter 6 Exercises: Inspect Specific GEO Series

In this exercise, you’ll retrieve metadata for the following GEO Series and answer:

GSE IDs: “GSE201427”,“GSE166530”,“GSE162183”,“GSE186458”

Questions per GSE

1. What type of data is it? Describe it. (platform technology; e.g., high-throughput sequencing, array)
2. What disease or model is it using? (infer from series title/summary/platform organism)
3. How many samples are there? What type of data is associated with the record?
4. How many control and how many disease?
5. **Can you find out any information about the GEO dataset - GSE264108. Why or Why not?

Hint: Sample labels are not standardized. Use robust keyword detection (e.g., control|normal|healthy|wild[- ]?type vs. tumou?r|cancer|patient|disease|mutant|treated). Inspect a few GSM rows if the automatic inference is uncertain.